Born Tolerant, Made Reactive: The Truth About How Skin Allergies Develop

By Entela Celiku, PhD Chemist in Natural Products, Your Scientific Voice at Kungul

I began my scientific journey as a natural products chemist, researching and isolating bioactive molecules derived from plants, herbs, and other natural sources. Like many in the field, I was fascinated by nature’s therapeutic potential and the powerful compounds it holds, lavender, chamomile, tea tree, and beyond. But as I delved deeper into cosmetic ingredient safety and toxicology, I uncovered a critical truth:

Natural doesn’t always mean safe.

In fact, some of the most common skin allergens today are natural compounds found in “clean beauty” products. And more and more people, especially those seeking healthier alternatives, are experiencing unexpected allergic reactions.

If you’ve ever used a skincare product labeled natural, organic, or safe for sensitive skin, and still ended up with a rash, itching, or burning… this blog is for you.

You’re Not Born Allergic. You Become Allergic.

Allergies don’t start on day one. Your body doesn’t react to something the first time it sees it, it learns. And over time, that learning can turn into an immune system overreaction.

This process unfolds in two stages:

  1. Sensitization phase: You use a product for months, even years. No symptoms. But your immune system is quietly registering a specific ingredient as a potential threat.
  2. Elicitation phase: Then, one day, your body reacts. A rash appears, maybe hours or even days later. And from that point on, even trace amounts of the ingredient can trigger inflammation, redness, or blisters.

What makes it even more confusing is that the reaction can seem random. You might assume it was stress, diet, or a single bad product. But often, it’s the result of repeated exposure to hidden allergens in your routine, especially fragrance compounds and essential oils.

The Natural Myth: Why “Clean” Skincare Can Still Be a Trigger

Take Andrea Salinas, for example, a health-conscious woman who used lavender-scented deodorant for years, thinking she was making a healthier choice. She even used lavender oil as a body spray. Then one day, she developed a rash that spread across her underarms and torso. Tests confirmed it: she had become allergic to lavender.

Andrea isn’t alone. Dermatologists across the U.S. and Europe are seeing increasing numbers of allergic contact dermatitis cases related to botanical ingredients like lavender, jasmine, peppermint, ylang-ylang, and tea tree oil.

And beyond allergies, some essential oils may pose deeper risks.
A recent study published in the Journal of Clinical Endocrinology & Metabolism linked lavender-containing products to abnormal breast growth in young girls and boys. Researchers discovered that certain components (α-Terpineol, Linalool)  in lavender and tea tree oils mimic estrogen and block testosterone, acting as endocrine disruptors. The symptoms disappeared once the products were removed, highlighting how even plant-derived ingredients can interfere with hormone function, especially in children.

This is not because these ingredients are “bad.” It’s because they are chemically complex and biologically active. They’re concentrated plant compounds, not inert plant water. And while they offer therapeutic properties, they can also penetrate the skin barrier and disrupt immune or hormonal balance, especially if your skin is already inflamed or sensitive.

How Does an Allergic Skin Reaction Work?

An allergic reaction happens when your immune system mistakes a substance, usually harmless, as a dangerous invader. The result? Skin inflammation. Redness. Itching. Blisters. Sometimes even peeling and pain.

This is different from irritation, which is more immediate and mechanical (like over-washing or using a harsh scrub). Allergies involve immune memory. Once your body decides something is a threat, it doesn’t forget. And every future exposure becomes a potential flare-up.

Some reactions appear as:

  • Allergic contact dermatitis: delayed inflammation after exposure to an allergen
  • Periorificial dermatitis: red, bumpy rashes around the nose, mouth, or eyes
  • Angular cheilitis: painful cracks in the corners of the mouth, often linked to allergens in lip care or toothpaste
  • Photosensitivity: where sunscreen ingredients or essential oils cause a rash after sun exposure

What makes it worse is that many ingredients capable of causing these reactions are poorly labeled or completely hidden under vague terms like fragrance or natural extract.

Where Allergens Are Hiding and How to Spot Them

As a chemist, I’ve studied the data, read the toxicology reports, and reviewed the formulations. And I can tell you that some of the most reactive ingredients in skincare are not where you’d expect them.

Here’s a table to help you recognize the most common allergens, where they appear, and how to spot them:

AllergenCommonly Found InHow to Spot It on the Label
FragrancesLotions, deodorants, sunscreens“Fragrance,” “parfum,” “perfume,” essential oils like linalool, limonene, geraniol
Essential oilsNatural/organic cosmeticsLavender, tea tree, peppermint, ylang-ylang, jasmine, lemongrass
ParabensCreams, makeup, face washMethylparaben, propylparaben, butylparaben
Formaldehyde-releasing agentsShampoos, baby wipes, creamsDMDM hydantoin, quaternium-15, imidazolidinyl urea, diazolidinyl urea
Methylisothiazolinone (MIT)Wet wipes, gels, liquid soaps“Methylisothiazolinone” or “MIT”
OxybenzoneChemical sunscreensLook for “oxybenzone” or other “-benzone” compounds
PropolisLip balms, natural creams“Propolis,” sometimes labeled as “beeswax”
LanolinLip products, baby ointments“Lanolin,” “wool wax,” or “wool grease”
PPD (p-phenylenediamine)Hair dyes, dark mascaras“PPD,” “p-phenylenediamine”
NickelShimmery or metallic eye makeupRarely listed—look for “nickel-tested” or avoid metallic finishes
FD&C dyesLipsticks, blushes, bright makeupFD&C Red 40, Yellow 5, Blue 1, etc.
Aluminum compoundsAntiperspirantsAluminum zirconium tetrachlorohydrex, aluminum chlorohydrate

Some of these allergens, like nickel or lanolin, might surprise you. Others, like MIT and quaternium-15, are still legal in many countries despite strong data showing high sensitization rate.

What You Should Do If Your Skin Reacts

If you develop a reaction, itching, swelling, stinging, or peeling, the most important step is to stop using all new or suspect products immediately. Simplify your routine. Use only gentle, fragrance-free cleansers and rich moisturizers with ceramides, which help restore the skin barrier.

Avoid hot water, scrubbing, or over-cleansing. Let your skin calm down. Resist scratching, even if the itch feels unbearable, it only worsens inflammation and delays healing. If your reaction doesn’t improve within a week, or spreads, seek help from a dermatologist. In severe cases (facial swelling, throat tightness, difficulty breathing), seek medical care immediately.

And always remember: allergic skin reactions may look small on the surface, but they signal a larger shift in your body’s immune memory. Prevention is much easier than treatment.

What Kungul Can Do For You

That’s where Kungul comes in. Our app was built to help you identify harmful, allergenic, or suspicious ingredients, quickly, clearly, and without any brand bias.

By scanning the products you already use, or want to try, Kungul gives you:

  • A full breakdown of the ingredient list
  • Safety ratings backed by scientific and regulatory data
  • Real insight into allergens, endocrine disruptors, irritants, and more
  • Carefully selected products you can find on kungulapproved.com, offering better, safer choices tailored to your skin’s needs.

And the best part? We’re constantly updating our database, now over 400,000 products analyzed so you always stay ahead of hidden threats.

Final Thought: Nature Is Powerful. Use It With Respect.

I still believe in the value of natural products. I still use them in my daily life. But I use them with understanding, not blind faith. And I want to help you do the same. Your skin is not overreacting. It’s speaking to you.

And at Kungul, we’re here to help you listen, through science, transparency, and care.

Download the Kungul app, scan your products, and feel confident in every choice you make.

With scientific care,

Dr. Entela Celiku

more articles